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Crawled under a rock, Electric blanket cranked to the highest and herbal tea hot toddy style, chicken broth, water, Motrin

Maes M, Mihaylova I, Leunis JC

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Although this remains to be confirmed, one possibility is that Ator1, adjacent to the pore-forming domain, binds with the highest affinity, as it requires only minimal conformational changes in RyR1 to allow its binding