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1) Post-exertional malaise (PEM) Post exertional malaise means symptoms worsen after minor physical or mental activity

Exercise has been known to attenuate oxidative stress and improve diabetic complications due to its effects on mitochondrial carbohydrate and lipid metabolism ( Our earlier study on GK rats subjected to moderate exercise training has shown improvement in cardiac muscle contractile dysfunction and relaxation in myocytes, which are relevant to improvement in diabetes-induced myocardial dysfunction ( Exercise training is recognized as an important non-therapeutic strategy in the management of type 2 diabetes, and studies have shown its effects on mitochondrial metabolic, oxidative, and redox functions in different tissues

Rivera, C