The effect of GLP-1R agonists liraglutide and exendin-4 was examined in vivo on CD-1, MCF-1, MDA-MB-468, MDA-MB-231, 4T1, LNCap, PANC-1, MIA PaCa-2, CT26, SKOV-3, and Apc(Min/+) cell lines expressed in cancers such as thyroid, breast, prostate, pancreatic, colon, ovarian, intestinal, and liver (Table 2)
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Editorial Advisory Board Member, Harvard Health Publishing GLP-1 drugs for diabetes and weight loss have proven to be very effective, but they do have side effects
Centrally, GLP-1, primarily produced by neurons in the nucleus of the solitary tract (NTS), modulates appetite and body weight through widespread neural projections (19,20)