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Solution dilution is the single highest-impact modification
Single-nuclei transcriptomes from sALS and C9orf72 ALS revealed that C9orf72 hexanucleotide repeat expansion impairs the microglial cell state transition to activated state compared to sALS (Masrori et al., 2025)
ALC boosts mitochondrial metabolism and energy production by facilitating carnitine shuttling and fatty acids beta-oxidation [156-158]
We included consecutive patients with late window stroke due to M2 occlusion, baseline NIHSS score 5 and premorbid mRS score 2 who received EVT or MM alone
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