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Cumulative transposon insertions per gene were then compared statistically between the infected and uninfected samples (with the reference library as a baseline to filter out poorly represented, presumably essential genes) using the same data analysis procedure as for the AG screen, albeit with two biological replicates instead of three

They play a crucial role in trans-endothelial migration of lymphocytes, monocytes, and neutrophils, as well as in cell signaling and transcriptional regulation [19,20,21]

Cellular senescence in cancer: clinical detection and prognostic implications