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These changes were statistically significant, and the direction of effect suggests possible neuroprotection, but the magnitude was very small (particularly if we compare these results to those in the Phase 3 trials of AD drugs that are now approved, such as lecanemab or donanemab) , the sample limited, and there is no evidence these shifts translate into meaningful clinical benefit

Subcutaneous administration was associated with a somewhat better outcome compared to oral semaglutide

Semaglutide and tirzepatidethese drugs are all the rage right now