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As we stated in the proposed rule, requiring the median rather than the average is consistent with generally accepted statistical principles for assessing the central point of a distribution when there are outliers

Conclusions and perspective The GSH system is one of the most significant members of the cellular antioxidant defensive system, which is essential for eliminating excess ROS and protecting the myocardium in the presence of pathological cardiovascular factors

The individual evidence for each compound is substantial and replicated in animal research, but the rationale for pairing them is mechanistic: it is based on what each does on its own, not on a study of the combination

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