retatrutide phase 2 trial type 2 diabetes Delivers Significant Hemoglobin A1C Reduction, Weight Loss in 3 VisualAbstract: Retatrutide reduces body weight

Side effects and safety considerations The most common side effects of GLP-1 medications are gastrointestinal and include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort

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Side Effects and Safety Considerations GLP-1 receptor agonists are generally well-tolerated, but patients should be aware of potential adverse effects and safety considerations before starting treatment for PCOS

Several preclinical and animal studies have suggested that GLP-1RAs may have neurotrophic and neuroprotective effects, by reducing neuroinflammation, oxidative stress, apoptosis, and mitochondrial dysfunction and by promoting the growth and repair of neural cells, potentially enhancing cognitive functions [73,74,75]