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6: Your prescriber may not be experienced with obesity medicine A 2025 cross-sectional study published in Obesity Medicine found that patients treated by an obesity specialist were 8 times more likely to remain on GLP-1 therapy than patients treated in general care settings (Liu et al., 2025)

another form of semaglutide, Rybelsus, is a daily pill

Indeed, several recent studies using perioperative GLP-1 agonists have demonstrated improved glycaemic control and reduced insulin requirements in cardiac and non-cardiac surgeries without increase in hypoglycaemia or other adverse events

271,272 Additionally, hyperglycemia-induced oxidative and nitrosative stress activates poly(ADP-ribose) polymerase (PARP), a nuclear enzyme involved in DNA repair