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Consequently, patience during reconstitution protects the integrity of all four compounds simultaneously

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For patients who want faster or more dramatic results, GLP-1 medications like semaglutide and tirzepatide have been shown in clinical trials to help patients lose 15% to 25% of their body weight over 12 to 18 months

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Several possible reasons may explain the benefit

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When tirzepatide activates these renal GLP-1 receptors, it increases sodium excretion, a process called natriuresis

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