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In this way, supporting liver detoxification with glutathione may help break the chemical feedback loop that drives the debilitating symptoms of POTS and dysautonomia

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For example, studies performed in murine J774A.1 macrophages showed that TMAO induced stress and led to increased protein expression of GRP94 and HSP70, which may participate in the abnormal activation of macrophages involved in foam cell formation (Mohammadi et al., 2018)