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To investigate the impact of ACE2 gene variants on the antidepressant efficacy of SSRIs, a randomized, controlled trial was completed, involving 200 patients with newly diagnosed depression who underwent fluoxetine or sertraline for 6 weeks, along with ACE2 allele genotyping (71)

Another study found that those who participated in high-intensity interval training (HIIT) reported significant improvements in sleep quality and moderate improvements in sleep efficiency (the amount of time in bed actually spent sleeping) [23]

A higher gauge number means a thinner needle (e.g., 31G is thinner than 29G)

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