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119 The miR-590-3p secreted by M2 macrophage exosomes is transferred from macrophages to intestinal epithelial cells, activating the YAP/-catenin pathway and thereby promoting the proliferation of intestinal epithelial cells and wound healing and alleviating intestinal mucosal injury

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L-histidine, on the other hand, is an essential amino acid present in serum and serves as a proteinogenic precursor with bioactive properties (Figure 1) [13]