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( 3.1.6 Role of NADPH oxidase in ferroptosis NOX, a widely distributed membrane protein in humans, represents the only enzyme capable of directly catalyzing ROS generation ( 3.1.7 Voltage-dependent anion channels in ferroptosis and oxidative stress Voltage-dependent anion channels (VDACs), membrane pore proteins located in the outer mitochondrial membrane, facilitate ion and metabolite transport in eukaryotic cells ( 3.2 Ferroptosis and lipid peroxidation 3.2.1 Definition and mechanism of lipid peroxidation Lipid peroxidation represents a process triggered by excess ROS, involving oxidative generation of polyunsaturated fatty acid phospholipids (PUFA-PE)

[1] [2] Administered as a once-weekly subcutaneous injection, Ozempic has demonstrated significant efficacy in improving glycaemic control in clinical trials

Medical supervision significantly lowers the risk of complications

demonstrated the potential of notochordal cells in preventing IVD degeneration in a white rabbit model