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In a preclinical TBI model, ablation of this progression through antibiotic depletion of gut microbiota attenuated CA-1 (but not CA-3) neuronal loss, microgliosis, and associative learning deficits induced by CCI [112]

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Complementary DNA was synthesized using the PrimeScript RT Kit (RR037A, Takara)

Suboptimal intakes or deficiencies of vitamins, minerals and fatty acids can be assessed through dietary recall and/or laboratory testing, although both have limitations and may not accurately identify treatment responders, and nutrients may have pharmacological effects independent of deficiency or low dietary intake