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pH-sensitive TfR bispecific antibodies (e.g., pH-PEG engager-TfR) dissociate PEG-NPs in acidic endosomes, boosting liposomal doxorubicin brain accumulation 2-3x in GBM xenografts (139)

2 Every FSA/HSA plan is unique, and Noom does not provide medical, healthcare benefit, or tax advice to individuals

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Cells were gated for singlets, and the GeoMean NAO, TMRE or MitoSOX Red fluorescence was evaluated using FlowJo software