glp-1 medications long term side effects of Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with Receptor Agonists: A Multidisciplinary Expert Consensus Comparing GLP‑1 Drugs With Other – Is Ozempic a GLP-1 Medication?

Laboratory Abnormalities Liver Enzymes Increases in alanine aminotransferase (ALT) greater than or equal to 10 times the upper limit of normal were observed in 5 (0.15%) SAXENDA-treated patients (two of whom had ALT greater than 20 and 40 times the upper limit of normal) compared with 1 (0.05%) placebo-treated patient during the SAXENDA clinical trials

Other consumers may decide to stop taking the GLP-1s and opt for less expensive health and weight management alternatives, which could benefit retailers that sell dietary supplements and health-focused foods

For example, once-a-day orforglipron was associated with a 14.7% body weight loss after 36 weeks in overweight/obese patients

1 This trial demonstrated clinically meaningful reductions in body weight after 68 weeks of treatment