Contrariwise, other relevant aspects, such as the safety profile and tolerability of GLP-1RA or the beneficial effects on fertility in PCOS, have been more extensively treated, especially considering that possible direct or indirect reproductive effects of GLP-1 RA might require a concomitant effective contraception and a washout period before pregnancy [22, 24,25,26,27,28,29,30,31]
Additionally, Roches growing digital health portfolio (patient-facing AI tools, chatbot assistants) relies on SAP-grade conversational AI
A similar trend was observed in the STEP 1 trial of 2021
Healthcare professionals should emphasise the importance of adequate protein intake and resistance exercise alongside any weight loss intervention to preserve lean body mass