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Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

- Biological age reflects how your cells are aging based on biomarkers such as DNA methylation, oxidative stress, and metabolic efficiency

Review of high-risk factors Previous studies have shown that the development of DILI depends not only on the offending drug but also on host-related risk factors, including advanced age, female sex, pre-existing or concomitant liver disease, metabolic syndrome and diabetes, heavy alcohol use, polypharmacy, and genetic susceptibility mediated by specific HLA alleles (47)

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