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Enzymes like glutathione reductase, ascorbate peroxidase, glutathione peroxidase and glutathioneS-transferase also showed altered activities in the affected tissues
Kern and Jones have summarized the important role of Purkinje cell abnormalities in autism, especially the susceptibility of these cells to oxidative stress during GSH depletion
Recent research indicates that these risks may be more closely associated with progestogens, given that contraceptives containing both estrogen and progestogen, as well as progestogen-only formulations, have been shown to elevate the risk of breast cancer (166, 167)