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Lancet 398(10317):21602172 Qiu W et al (2023) Multiple NTS neuron populations cumulatively suppress food intake

In placebo-controlled trials evaluating semaglutide used as monotherapy and as an add-on to insulin glargine, treatment with semaglutide resulted in statistically significant reductions in glycosylated HbA 1C of 1.2% to 1.4% and 1.1% to 1.6% respectively, compared with placebo