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Description

TBK1 then phosphorylates and activates both the IRF3 pathway and the NF-B pathway, triggering the transcription of proinflammatory cytokines, antiviral chemokines, interferon-stimulated genes (ISGs), and type I IFNs

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For instance, HSCs facilitate the progression of HCC by regulating histone acetylation within the TME (118)

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