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Robert Kushner, a principal investigator on multiple STEP trials, stated in a 2023 JAMA editorial: "The cost barrier remains the single largest impediment to appropriate utilization of GLP-1 receptor agonists for obesity, particularly in states without Medicaid coverage mandates" 27

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Ninety percent of the AIA-positive patients on TOUJEO with antibody test at baseline, remained AIA positive at month 6