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The randomized, double-blind, placebo-controlled trial by Depommier et al., 2019 demonstrates low risk of bias overall, with clearly defined eligibility criteria, intervention protocols, and prespecified outcomes

The purple-crimson color of beetroot powder is due to betalains, which include betacyanin, the primary pigment of beets

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4.4 Effects on renal hemodynamics and systemic metabolism The interaction between metabolic shifts and renal hemodynamics/tubuloglomerular feedback (TGF) is one of the core mechanisms of AKI, which involves imbalance of energy metabolism, accumulation of metabolites, oxidative stress, inflammation and regulation of signal pathways (Wada et al., 2024