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NAD is a coenzyme involved in cellular energy production across many pathways

This includes some heartburn medicines including proton pump inhibitors (PPIs) such as rabeprazole, omeprazole, esomeprazole, lansoprazole and pantoprazole

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For the last two decades, skeletal muscle was the main target of therapy [40], and drug discovery programs focused on strategies to inhibit the muscle catabolic pathways and stimulate the anabolic pathways [52]