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When it declines, the systems that tell you "you're full" become less effective [11, 3]

Metabolic health is a term describing how well the body processes and generates energy, which clinicians assess based on five biomarkers: Waistline circumference Fasting glucose High-density lipoprotein (HDL) cholesterol (aka good cholesterol) Triglycerides Blood pressure Clinicians consider a person to be metabolically healthy if all these metrics are in the normal range

-arrestin recruitment assay PathHunter CHO-GLP-1R -arrestin-1 and -2 reporter cell lines were used, following the manufacturers instructions

Cell 183 , 11431146 (2020)