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Cost Implications of Dose Escalation Flat-Rate Model: Month 1-2 (2.5-5 mg): Pay: $349/month Medication cost: ~$100-160/month Other services: ~$150-200/month Provider margin: Low to moderate Month 6-12+ (12.5-15 mg): Pay: $349/month (same) Medication cost: ~$260-400/month Other services: ~$100-150/month Provider margin: Low to none Flat-rate means early months subsidize later monthsfair over full treatment course

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Localization and chemical forms of cadmium in plant samples by combining analytical electron microscopy and X-ray spectromicroscopy