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Low to moderate-intensity exercise lasting 4 weeks improved depression-like behavior in mice and increased neuronal proliferation, differentiation, and survival in the hippocampus, correlated with elevated hippocampal FNDC5/irisin levels post-exercise (Siteneski et al., 2020)

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107 Notably, hypomagnesemia has been identified in individuals with T2DM, particularly those with inadequate glycemic control

BPC 157 strongly improved the MPTP-impaired somatosensory orientation and reduced the MPTP-induced hyperactivity, and most importantly, MPTP-motor abnormalities (tremor, akinesia, catalepsy -otherwise very prominent in saline control), leading to almost complete abolition of otherwise regularly lethal course of MPTP treatment in controls