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Description

From a therapeutic perspective, understanding the hierarchical model has led to the development of CSC-targeted drug screening approaches, which specifically assess compounds on the basis of their ability to eliminate both proliferating and quiescent CSCs

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Amand M, Adams P, Schober R, Iserentant G, Servais J-Y, Moutschen M, et al

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363,364 This inhibition is believed to occur through the suppression of LPS-induced TNF- production in macrophages

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Neuronal oxidative stress promotes -synuclein aggregation in vivo

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