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As an antioxidant, glutathione enables precise direct or indirect control of ROS (such as singlet oxygen, superoxide anions, hydrogen peroxide, etc.), which often accumulate/produce at high levels during biotic stress, thereby reducing damage to the cells (Zechmann, 2020)

Further research is needed to elucidate the circumstances, specific molecular targets, other enzymes involved in the signaling process, and to map the involvement of GSH in redox signaling pathways ( An emerging area of research is that of immune memory in the brain ( Because of the importance of GSH in many cellular and immunological processes and its potential as a biomarker, accurate measurement and analysis of GSH levels are critical to further research and analysis of its efficacy as a treatment

An increasing number of studies have shown that in the early stages of IBD, natural polyphenols can effectively reduce the severity of intestinal inflammation and oxidative stress (218)