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Studies have shown that GLP-1 receptors play important roles in the cardiovascular system such as adjusting of the heart rate, blood pressure, vascular tone and myocardial contractility 3

Since, no diffusional barrier exists in between CSF and nervous tissues interstitial space, even larger size may be able to enter up to the interstitial space by diffusion in the vicinity of CSF existence, but may not be able to be taken up by neuronal cells [43]

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Other ROS, including hydrogen peroxide ( H2O2 ) are not, technically speaking, free radicals, but are nevertheless highly reactive