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This approach improves GHK-Cu peptide bioavailability in the central nervous system and avoids potential toxicity associated with systemic copper overload

& Patel, D

In explaining what has contributed to this consideration, we identified the importance of balancing our goal of driving the greatest possible shift to high-value care delivery, which we believe may be incentivized most effectively under a two-sided model, with a concern that requiring ACOs to take on too much downside risk too quickly may disincentivize program participation and reduce the program's potential to positively affect the quality and cost of care furnished to beneficiaries

289: L1131-L1137