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Remarkably, it has been demonstrated that mitochondria can be recruited to presynaptic boutons in response to elevated neuronal activity and contribute to rescaling synaptic excitability to match the neuronal stimulation [56]
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Analysis of adverse effects (OR = 0.03, 95% CI: 0.030.09) revealed comparable safety profiles, with reported events primarily consisting of gastrointestinal symptoms (abdominal pain, nausea, reflux, diarrhea, constipation, flatulence, and indigestion), neurological effects (headache and daytime drowsiness), and occasional hypersensitivity reactions or cold sores
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