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Thus, we find that these two molecules have advanced in different areas: Melanotan-1 (SCENESSE, Clinuvel Pharmaceuticals Ltd) is being studied in phase 2 and phase 3 clinical trials as a photoprotective drug for protection against nonmelanoma skin cancer and in other photoinduced skin diseases, such as erythropoietic protoporphyria, solar dermatitis, and polymorphic light eruption
The rationale was the effect on decreasing the lower esophageal sphincter tone
Sensitivity of vagal mucosal afferents to cholecystokinin and its role in afferent signal transduction in the rat
doi: 10.1016/0005-2736(81)90528-9
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