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70-80% of immune cells are located in the gut

has received consultancy and/or lecture fees from companies with an interest in developing and marketing incretin-based therapies for treatment of type 2 diabetes mellitus (Boehringer Ingelheim, Lilly, Merck/MSD and Novo Nordisk)

nonetheless, this overexpression approach might alter receptor distribution or signalling, and constitutes a limitation of the model

This, combined with reduced antioxidants such as glutathione and glutathione peroxidase (GPx), increases granulosa cell susceptibility to ferroptosisan iron- and reactive oxygen species (ROS)-dependent programmed cell deathultimately impairing oocyte maturation and competence