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Lower back pain, changes in urination, swelling in the legs or feet, and unusual fatigue are warning signs

= exceeds 28-day window per reconstitution Solution: If you're running maintenance only, reconstitute in two batches (add less water the second time) or plan a short loading phase to use the first batch within 28 days

Glutamine, glycine, aspartate, 10-formyl THF, and CO 2 are used as substrates for the synthesis of inosine monophosphate (IMP)the intermediate product of AMP and GMP (Figure 1)