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Gastrointestinal Protection Research : Research evaluates protective effects on the digestive tract, particularly under conditions of stress or chemical irritation

[25] Those experiencing recurrent hypoglycaemia, severe gastrointestinal symptoms, or concerning new symptoms should contact their GP or diabetes specialist team promptly

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Mechanistically, we reveal that tirzepatide restores -cell function by rescuing FOXO1 signaling, which in turn up regulates the expression of PDX1 and MAFA, thereby reversing -cell dedifferentiation and re-establishing cell identity