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Complete resolution of symptoms is often needed before resuming

Adults experiencing fatigue, muscle loss, poor recovery, or age-related hormonal decline often benefit most from peptide therapy for metabolism and fat loss

131 This is consistent with the data in humans showing that a low-protein diet (5E% protein) increased plasma FGF21 concentrations by 171% over 4 weeks despite caloric overfeeding

Mod GRF 1-29 Research Direct clinical trial data for Mod GRF 1-29 specifically is more limited, though the broader class of GHRH analogs (including the parent compound sermorelin, which is FDA-approved for GH deficiency diagnosis) is well-studied