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instead, GLP- 1 receptor activation stimulates EGF receptor signaling [20]

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Many patients are on a combination of an SGLT2 inhibitor with a GLP-1 receptor agonist or tirzepatide (a dual agonist) and have incredible success without adverse reactions, but we are still figuring out the patient characteristics that would put them at higher risk of poor outcomes. Eli J

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In 2015, obesity was estimated to have accounted for four million deaths globally, two-thirds of which were caused by CVD

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