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For DPP-4 inhibitors (phase III studies), it was 0.753 (95% CI 0.412, 1.374, p = 0.355), and for DPP-4 inhibitors (including results from recent outcome studies), it was 1.095 (95% CI 0.738, 1.625, p = 0.652)

doi: 10.1196/annals.1294.015 100 KonsoulaZ.BarileF

The binding modes of the clinically most widely used DPP-4 inhibitors have been characterized and based on these findings, three different classes of DPP-4 inhibitors have been proposed: Class 1 comprises of saxagliptin and vildagliptin, interacting with the S1- and S2 subsites of the active center and covalently binding with Ser630 of the DPP-4 molecule

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