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Research advances in the use of histone deacetylase inhibitors for epigenetic targeting of cancer

But Wenz says researchers are still learning about less-obvious benefits of metformin

While there is good evidence to support this idea in model organisms such as Drosophila melanogaster and Caenorhabditis elegans , [68] [69] recent evidence from Michael Ristow's laboratory suggests that oxidative stress may also promote life expectancy of Caenorhabditis elegans by inducing a secondary response to initially increased levels of reactive oxygen species

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