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After scratching the cells to make a wound, 3 10 9 particles of fluorescently labeled l-EVs were added to the 4 10 6 cells in 200 l of phenol red-free DMEM medium (Gibco, #21063029) containing 10% EV-depleted FBS, and the cells were incubated for 1 h before the observation

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Reduced release of fatty acids and glycerol from adipose tissue directly links adipose tissue metabolism to that of the liver

The brownish-black macular lesion on the left buccal mucosa was well demarcated from the surrounding mucosa with regular, well-defined borders