or BMI 27 kg/m with at least one indicator of increased cardiovascular risk (e.g., coronary heart disease, hypertension, dyslipidemia, diabetes, elevated waist circumference), or another obesity-related medical condition (e.g., sleep apnea)
Further trials exploring the combination of the NPY inhibitor and orlistat were also disappointing and have been discontinued [96]
Foods high in antioxidants and omega-3 fatty acids, such as seafood and green leafy vegetables, are also beneficial. Options include: Mediterranean-style eating: plant-based foods, healthy fats Soy-based foods: tofu, edamame, soy milk, tempeh Phytoestrogen-rich foods: whole grains, seeds, legumes, berries Omega-3: salmon, chia seeds, avocados, flaxseeds Naturally cooling foods: apples, bananas, carrots, cucumbers, watermelon, pears, romaine lettuce Mediterranean-style eating can be a practical place to start
Genetic engineering opened up a new way to manufacture human proteins previously difficult to obtain in large quantities
