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In non-malignant cells, Nrf2 activation induces the transcription and expression of antioxidant target genes, which can resist genetic damage and physical and chemical carcinogens caused by oxidative stress (Villanueva, 2019)

Endoplasmic reticulum stress promotes blood-testis barrier impairment in mice with busulfan-induced oligospermia through PERK-eIF2 signaling pathway

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