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Splitting, chewing, or crushing the tablet also breaks down this barrier, making the drug less effective

Garlic in particular contains allicin and other sulfur compounds that have been shown to support cellular glutathione levels

In addition, animal, observational, and genetic studies suggest benefits of GLP-1RAs in people with alcohol use disorder, although randomized trials have produced mixed results, with ongoing trials assessing their effectiveness in those with substance use disorders (SUDs) and mental illnesses