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Conclusion: Combined application of the iron-chelating antioxidants such as acetyl-L-carnitine and astaxanthin is beneficial in the treatment of Parkinsons disease, which are due to its Iron-chelating antioxidant, Antionflamamtory, Poly(ADP-Ribose)Polymerase Inhibitory (PARP-1-I) and Neuronal Genome Stabilizing Effects

However, this study has notable clinical limitations: The second cohort (Cohort 2) only included 24 patients, confounding factors such as diet and concurrent medications were not adjusted for, and there is a lack of clinically standardized protocols for MDSC function detection

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