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Gastrointestinal (GI) symptoms such as nausea, vomiting, constipation, and diarrhea are the most common adverse effects of GLP-1 therapies and are a leading cause of treatment discontinuation

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At 88 days of age vehicle, 25 nmol/kg and 75 nmol/kg dosed animals weighted 17.1 0.9 g, 17.8 1.1 g and 17.6 1.2 g respectively (overall P = 0.3165, two-way ANOVA with repeated measures)

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