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(11) Tesamorelin & Ipamorelin and Cognitive Improvement Studies have indicated that growth hormone and its secretagogues, such as Tesamorelin and Ipamorelin, might play a role in neuroplasticity, neuronal survival, and synaptic plasticity, all of which are considered critical for optimal cognitive performance

That this finding was only observed in the DLPFC (and not the ACC) in our cohort is in line with research observing frontal cortical thinning in blast exposed veterans (59), decreased activity (60), and white matter damage (61) in the PFC following mTBI

Animal studies have demonstrated that a single administration can induce synaptogenic effects-promoting the growth of synapses-that persist for 7 to 14 days

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