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Lancet Diabetes Endocrinol (2019) 7:51527

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We then treated these cells with a low dosage of erastin, the inhibitor of cysteine transporter xCT 38 , which drastically reduced GSH level and induced replication stress (Fig.7f, g)

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Up to 30% of patients were shown to have abnormal epidermal nerve fiber density in the calf and skin

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