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Butyrate and propionate both have been associated with the prevention of various allergic diseases and, consequently, high faecal levels of these fatty acids in early life have been associated with a decreased risk of developing atopy (207209)

Also the NHS, the UK healthcare system, mentions that both B12 deficiency and folate deficiency are affecting around 1 in 10 people aged 75 or over and 1 in 20 people aged 65 to 74

This means that for any two points in the domain, the function value at an intermediate point is at least as large as the corresponding secant line value

Endothelial dysfunction, which can be detected by the reduction in vascular responsiveness to vasodilators, is a major contributing factor to diabetic cardiovascular complications